FRAT1 Polyclonal Antibody
- 货号:YN0202
- 应用:WB;ELISA
- 种属:Human;Mouse
- 简介:
- >>Wnt signaling pathway;>>Alzheimer disease;>>Pathways of neurodegeneration - multiple diseases;>>Pathways in cancer;>>Breast cancer;>>Hepatocellular carcinoma;>>Gastric cancer
- 蛋白名称:
- Proto-oncogene FRAT1 (Frequently rearranged in advanced T-cell lymphomas 1) (FRAT-1)
- 免疫原:
- Synthesized peptide derived from human protein . at AA range: 130-210
- 特异性:
- FRAT1 Polyclonal Antibody detects endogenous levels of protein.
- 组成:
- Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500-2000 ELISA 1:5000-20000
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 背景:
- The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis. [provided by RefSeq, Oct 2008],
- 功能:
- function:Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.,PTM:Phosphorylated.,similarity:Belongs to the GSK-3-binding protein family.,subunit:Binds DVL1. Binds GSK-3 and prevent GSK-3-dependent phosphorylation.,
![](/uploadfiles/PIC/YN0202wb-2020.jpg)
- Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night