GSK3α (PT0374R) PT® Rabbit mAb
- 货号:YM8225
- 应用:WB;IHC;IF;IP;ELISA
- 种属:Human; Mouse; Rat;
- 靶点:
- GSK3α
- 简介:
- >>Chemokine signaling pathway;>>Dopaminergic synapse;>>Non-alcoholic fatty liver disease;>>Shigellosis
- 基因名称:
- GSK3A
- 蛋白名称:
- Glycogen synthase kinase-3 alpha
- Human Gene Id:
- 2931
- Human Swiss Prot No:
- P49840
- Mouse Gene Id:
- 606496
- Mouse Swiss Prot No:
- Q2NL51
- Rat Gene Id:
- 50686
- Rat Swiss Prot No:
- P18265
- 特异性:
- endogenous
- 组成:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- 来源:
- Monoclonal, rabbit, IgG, Kappa
- 稀释:
- IHC 1:200-1:1000,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200,
- 纯化工艺:
- Protein A
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- GSK3A;Glycogen synthase kinase-3 alpha;GSK-3 alpha;Serine/threonine-protein kinase GSK3A
- 分子量:
- 51kD
- 实测条带:
- 51kD
- 背景:
- glycogen synthase kinase 3 alpha(GSK3A) Homo sapiens This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011],
- 功能:
- catalytic activity:ATP + [tau protein] = ADP + [tau protein] phosphate.,function:Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer.,
- 细胞定位:
- Cytoplasm
- 组织表达:
- Brain,Eye,Foreskin,Lung,Pancreas,Platelet,Testis,
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- Antibody-FAQs
- 产品图片
- Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-GSK3α (PT0374R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: K562 Lane 2: Hela Lane 3: Mouse brain Lane 4: Rat brain Predicted band size: 51kDa Observed band size: 51kDa
- Human breast carcinoma was stained with anti-GSK3α (PT0374R) rabbit antibody