GSK3α (PT0374R) PT® Rabbit mAb

    • 货号:YM8225
    • 应用:WB;IHC;IF;IP;ELISA
    • 种属:Human; Mouse; Rat;
      • 靶点:
      • GSK3α
      • 简介:
      • >>Chemokine signaling pathway;>>Dopaminergic synapse;>>Non-alcoholic fatty liver disease;>>Shigellosis
      • 基因名称:
      • GSK3A
      • 蛋白名称:
      • Glycogen synthase kinase-3 alpha
      • Human Gene Id:
      • 2931
      • Human Swiss Prot No:
      • P49840
      • Mouse Swiss Prot No:
      • Q2NL51
      • 特异性:
      • endogenous
      • 组成:
      • PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
      • 来源:
      • Monoclonal, rabbit, IgG, Kappa
      • 稀释:
      • IHC 1:200-1:1000,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200,
      • 纯化工艺:
      • Protein A
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • GSK3A;Glycogen synthase kinase-3 alpha;GSK-3 alpha;Serine/threonine-protein kinase GSK3A
      • 分子量:
      • 51kD
      • 实测条带:
      • 51kD
      • 背景:
      • glycogen synthase kinase 3 alpha(GSK3A) Homo sapiens This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011],
      • 功能:
      • catalytic activity:ATP + [tau protein] = ADP + [tau protein] phosphate.,function:Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer.,
      • 细胞定位:
      • Cytoplasm
      • 组织表达:
      • Brain,Eye,Foreskin,Lung,Pancreas,Platelet,Testis,
      • 产品图片
      • Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-GSK3α (PT0374R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: K562 Lane 2: Hela Lane 3: Mouse brain Lane 4: Rat brain Predicted band size: 51kDa Observed band size: 51kDa
      • Human breast carcinoma was stained with anti-GSK3α (PT0374R) rabbit antibody