Rab 5A (PT0309R) PT® Rabbit mAb

    • 货号:YM8182
    • 应用:WB;IHC;IF;IP;ELISA
    • 种属:Human; Mouse; Rat;
      • 基因名称:
      • >>Ras signaling pathway;>>Endocytosis;>>Phagosome;>>Vasopressin-regulated water reabsorption;>>Amyotrophic lateral sclerosis;>>Pathways of neurodegeneration - multiple diseases;>>Salmonella infection;>>Amoebiasis;>>Tuberculosis
      • 蛋白名称:
      • RAB5A
      • 序列:
      • Ras-related protein Rab-5A
      • Human Gene Id:
      • 5868
      • Human Swiss Prot No:
      • P20339
      • Mouse Swiss Prot No:
      • Q9CQD1
      • 特异性:
      • endogenous
      • 组成:
      • PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
      • 来源:
      • Monoclonal, rabbit, IgG, Kappa
      • 稀释:
      • IHC 1:1000-1:4000,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200,
      • 纯化工艺:
      • Protein A
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • RAB5A;RAB5;Ras-related protein Rab-5A
      • 分子量:
      • 24kD
      • 实测条带:
      • 24kD
      • 背景:
      • enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP.,function:Required for the fusion of plasma membranes and early endosomes.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Enriched in stage I melanosomes.,subunit:Binds EEA1. Interacts with RIN1 and GAPVD1, which regulate its pathway, probably by acting as a GEF. Interacts with ALS2CL, UNC84B, ZFYVE20 and RUFY1. Interacts with SGSM1 and SGSM3.,
      • 功能:
      • enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP.,function:Required for the fusion of plasma membranes and early endosomes.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Enriched in stage I melanosomes.,subunit:Binds EEA1. Interacts with RIN1 and GAPVD1, which regulate its pathway, probably by acting as a GEF. Interacts with ALS2CL, UNC84B, ZFYVE20 and RUFY1. Interacts with SGSM1 and SGSM3.,
      • 细胞定位:
      • Cytoplasm, Membrane
      • 组织表达:
      • Brain,Cervix,Cervix carcinoma,Placenta,
      • 产品图片
      • Rat kidney was stained with anti-Rab 5A (PT0309R) rabbit antibody
      • Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Rab 5A (PT0309R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: HepG2 Lane 2: Jurkat Lane 3: C6 Lane 4: Neuro-2a Predicted band size: 24kDa Observed band size: 24kDa
      • Human kidney was stained with anti-Rab 5A (PT0309R) rabbit antibody
      • Mouse kidney was stained with anti-Rab 5A (PT0309R) rabbit antibody