Rab 5A (PT0309R) PT® Rabbit mAb
- 货号:YM8182
- 应用:WB;IHC;IF;IP;ELISA
- 种属:Human; Mouse; Rat;
- 基因名称:
- >>Ras signaling pathway;>>Endocytosis;>>Phagosome;>>Vasopressin-regulated water reabsorption;>>Amyotrophic lateral sclerosis;>>Pathways of neurodegeneration - multiple diseases;>>Salmonella infection;>>Amoebiasis;>>Tuberculosis
- 蛋白名称:
- RAB5A
- 序列:
- Ras-related protein Rab-5A
- Human Gene Id:
- 5868
- Human Swiss Prot No:
- P20339
- Mouse Gene Id:
- 271457
- Mouse Swiss Prot No:
- Q9CQD1
- 特异性:
- endogenous
- 组成:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- 来源:
- Monoclonal, rabbit, IgG, Kappa
- 稀释:
- IHC 1:1000-1:4000,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200,
- 纯化工艺:
- Protein A
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- RAB5A;RAB5;Ras-related protein Rab-5A
- 分子量:
- 24kD
- 实测条带:
- 24kD
- 背景:
- enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP.,function:Required for the fusion of plasma membranes and early endosomes.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Enriched in stage I melanosomes.,subunit:Binds EEA1. Interacts with RIN1 and GAPVD1, which regulate its pathway, probably by acting as a GEF. Interacts with ALS2CL, UNC84B, ZFYVE20 and RUFY1. Interacts with SGSM1 and SGSM3.,
- 功能:
- enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP.,function:Required for the fusion of plasma membranes and early endosomes.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Enriched in stage I melanosomes.,subunit:Binds EEA1. Interacts with RIN1 and GAPVD1, which regulate its pathway, probably by acting as a GEF. Interacts with ALS2CL, UNC84B, ZFYVE20 and RUFY1. Interacts with SGSM1 and SGSM3.,
- 细胞定位:
- Cytoplasm, Membrane
- 组织表达:
- Brain,Cervix,Cervix carcinoma,Placenta,
- June 19-2018
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- June 19-2018
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- July 13-2018
- Antibody-FAQs
- 产品图片
- Rat kidney was stained with anti-Rab 5A (PT0309R) rabbit antibody
- Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Rab 5A (PT0309R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: HepG2 Lane 2: Jurkat Lane 3: C6 Lane 4: Neuro-2a Predicted band size: 24kDa Observed band size: 24kDa
- Human kidney was stained with anti-Rab 5A (PT0309R) rabbit antibody
- Mouse kidney was stained with anti-Rab 5A (PT0309R) rabbit antibody