EEA1 (PT0188R) PT® Rabbit mAb
- 货号：YM8117
- 应用：WB;IHC;IF;IP;ELISA
- 种属：Human; Mouse; Rat;
- 简介：
- >>Endocytosis;>>Phagosome;>>Tuberculosis
- 蛋白名称：
- Early endosome antigen 1
- 组成：
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- 来源：
- Monoclonal, rabbit, IgG, Kappa
- 稀释：
- IHC 1:100-200,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- EEA1;ZFYVE2;Early endosome antigen 1;Endosome-associated protein p162;Zinc finger FYVE domain-containing protein 2
- 背景：
- disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.,domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate.,function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 FYVE-type zinc finger.,subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding.,
- 功能：
- disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.,domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate.,function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 FYVE-type zinc finger.,subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding.,
- 组织表达：
- Aorta,Cervix carcinoma,Fetal brain cortex,Skeletal muscle,
- Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-EEA1 (PT0188R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.
Lane 1: C6
Predicted band size: 162kDa
Observed band size: 162kDa
- Various whole cell lysates were separated by 4-8% SDS-PAGE, and the membrane was blotted with anti-EEA1 (PT0188R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.
Lane 1: NIH-3T3
Lane 2: Hela
Predicted band size: 162kDa
Observed band size: 162kDa
- Human ductal breast carcinoma was stained with Anti-EEA1 (PT0188R) rabbit antibody
