• 靶点：
• Aurora A

• 简介：
• >>Oocyte meiosis;>>Progesterone-mediated oocyte maturation

• 基因名称：
• AURKA AIK AIRK1 ARK1 AURA AYK1 BTAK IAK1 STK15 STK6

• 蛋白名称：
• Aurora A

• Human Gene Id：
• 6790

• Human Swiss Prot No：
• O14965

• Mouse Gene Id：
• 20878

• Mouse Swiss Prot No：
• P97477

• Rat Swiss Prot No：
• P59241

• 特异性：
• endogenous

• 组成：
• PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• 来源：
• Monoclonal, rabbit, IgG, Kappa

• 稀释：
• IHC 1:200-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

• 纯化工艺：
• Protein A

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)

• 分子量：
• 45kD

• 实测条带：
• 45kD

• 背景：
• Aurora A(AURKA) Homo sapiens The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

• 细胞定位：
• Membranous

• 组织表达：
• Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.

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