Cytokeratin 15 (CK15) (ABT162R) rabbit mAb
- 货号：YM7257
- 应用：WB; ELISA
- 种属：Human;
- 简介：
- >>Estrogen signaling pathway;>>Staphylococcus aureus infection
- 蛋白名称：
- Cytokeratin 15 (CK15)
- 免疫原：
- Synthesized peptide derived from human Cytokeratin 15 (CK15) AA range:350-456
- 特异性：
- This antibody detects endogenous levels of Cytokeratin 15
- 组成：
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- 来源：
- Monoclonal, Rabbit IgG1, Kappa
- 稀释：
- WB 1:500-1000, ELISA 1:5000-20000
- 纯化工艺：
- Recombinant Expression and Affinity purified
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- AI528832;CK 15;CK-15;CK15;CytokeRatin-15;CytokeRatin15;K15;K1C15_HUMAN;K1CO;Ka15;KeRatin 15;KeRatin 15 basic;KeRatin 15 beta;KeRatin;KeRatin complex 1 acidic gene 15;KeRatin type I cytoskeletal 15;KeRatin-15;KeRatin15;KRT 15;Krt1-15;KRT15;KRTB;KRTL15;Type I cytoskeletal 15;Type I keRatin Ka15
- 功能：
- miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins.,tissue specificity:Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate.,
- 细胞定位：
- nucleus,intermediate filament,extracellular exosome,
- 组织表达：
- Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate.
- Immunohistochemical analysis of paraffin-embedded human Cervical squamous carcinoma. 1, Antibody was incubated at 4° overnight. 2, TRIS-EDTA of pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
