CDX-2 (ABT28R) rabbit mAb (Ready to Use)
- 货号：YM7078R
- 应用：IHC
- 种属：Human;
- 蛋白名称：
- Homeobox protein CDX-2 (CDX-3) (Caudal-type homeobox protein 2)
- 免疫原：
- Synthesized peptide derived from human CDX-2 AA range:150-265
- 特异性：
- This antibody detects endogenous levels of CDX2,CDX-1
- 组成：
- The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
- 来源：
- Monoclonal, Rabbit IgG1, Kappa
- 纯化工艺：
- Recombinant Expression and Affinity purified
- 其他名称：
- Caudal type homeo box 2 antibody;Caudal type homeo box transcription factor 2 antibody;Caudal type homeobox 2 antibody;Caudal type homeobox protein 2 antibody;Caudal type homeobox transcription factor 2 antibody;Caudal-type homeobox protein 2 antibody;CDX 2 antibody;CDX 3 antibody;CDX-3 antibody;Cdx2 antibody;CDX2/AS antibody;CDX2_HUMAN antibody;CDX3 antibody;Homeobox protein CDX 2 antibody;Homeobox protein CDX-2 antibody;
- 背景：
- This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012],
- 功能：
- function:Involved in the transciptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.,PTM:Phosphorylation of Ser-60 mediates the transactivation capacity.,similarity:Belongs to the Caudal homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
- 组织表达：
- Detected in small intestine, colon and pancreas.
