S100P (ABT375) mouse mAb (Ready to Use)
- 货号：YM6980R
- 应用：IHC
- 种属：Human;
- 蛋白名称：
- MIG9;Migration inducing gene 9;Protein S100-E;Protein S100-P;Protein S100P;S100 calcium binding protein P;S100 calcium-binding protein P;S100 P;S100E;S100P;S100P_HUMAN
- 免疫原：
- Synthesized peptide derived from human S100P AA range: 1-95
- 特异性：
- The antibody can specifically recognize human S100P protein.
- 组成：
- The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
- 来源：
- Mouse, Monoclonal/IgG1, kappa
- 纯化工艺：
- The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
- 其他名称：
- MIG9;Migration inducing gene 9;Protein S100-E;Protein S100-P;Protein S100P;S100 calcium binding protein P;S100 calcium-binding protein P;S100 P;S100E;S100P;S100P_HUMAN
- 背景：
- The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008],
- 功能：
- miscellaneous:This protein binds two calcium ions.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subcellular location:Colocalizes with S100PBP in the nucleus.,subunit:Homodimer. Interacts with S100PBP and S100Z.,tissue specificity:Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.,
- 细胞定位：
- Nuclear, Cytoplasmic
- Human pancreatic cancer tissue was stained with Anti-S100P (ABT375) Antibody
- Human placenta tissue was stained with Anti-S100P (ABT375) Antibody
