Calponin-1 (ABT133) mouse mAb (Ready to Use)
- 货号:YM6827R
- 应用:IHC
- 种属:Human;
- 免疫原:
- Synthesized peptide derived from human Calponin-1 AA range: 100-200
- 特异性:
- The antibody can specifically recognize human and mouse calponin-1 protein.
- 组成:
- The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
- 来源:
- Mouse, Monoclonal/IgG2a, kappa
- 纯化工艺:
- The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
- 其他名称:
- Calponin-1 (Basic calponin;Calponin H1, smooth muscle)
- 功能:
- function:Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.,similarity:Belongs to the calponin family.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 3 calponin-like repeats.,subunit:Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1.,tissue specificity:Smooth muscle, and tissues containing significant amounts of smooth muscle.,
- 组织表达:
- Smooth muscle, and tissues containing significant amounts of smooth muscle.
- Human appendix tissue was stained with anti-calponin-1(ABT133) antibody.
- Human smooth muscle tissue was stained with anti-calponin-1(ABT133) antibody.