Calponin-1 (ABT133) mouse mAb

    • 货号:YM6827
    • 应用:IHC;ELISA
    • 种属:Human;
      • 靶点:
      • Calponin-1
      • 基因名称:
      • CNN1
      • 蛋白名称:
      • Calponin-1
      • Human Gene Id:
      • 1264
      • Human Swiss Prot No:
      • P51911
      • 免疫原:
      • Synthesized peptide derived from human Calponin-1 AA range: 100-200
      • 特异性:
      • The antibody can specifically recognize human and mouse calponin-1 protein.
      • 组成:
      • PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
      • 来源:
      • Mouse, Monoclonal/IgG2a, kappa
      • 稀释:
      • IHC 1:200-400. ELISA 1:500-5000
      • 纯化工艺:
      • The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • Calponin-1 (Basic calponin;Calponin H1, smooth muscle)
      • 分子量:
      • 33kD
      • 实测条带:
      • 34kD
      • 功能:
      • function:Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.,similarity:Belongs to the calponin family.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 3 calponin-like repeats.,subunit:Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1.,tissue specificity:Smooth muscle, and tissues containing significant amounts of smooth muscle.,
      • 细胞定位:
      • Cytoplasmic
      • 组织表达:
      • Smooth muscle, and tissues containing significant amounts of smooth muscle.
      • 产品图片
      • Human appendix tissue was stained with anti-calponin-1(ABT133) antibody.
      • Human smooth muscle tissue was stained with anti-calponin-1(ABT133) antibody.