PAX-5 (PTR1332) mouse mAb (Ready to Use)

    • 货号:YM6693R
    • 应用:IHC
    • 种属:Human;Mouse;Rat;
      • 靶点:
      • MEK-4
      • 基因名称:
      • PAX5
      • 蛋白名称:
      • PAX-5
      • Human Gene Id:
      • 5079
      • Human Swiss Prot No:
      • Q02548
      • Mouse Swiss Prot No:
      • Q02650
      • 免疫原:
      • Synthesized peptide derived from human PAX-5 AA range:300-383
      • 特异性:
      • This antibody detects endogenous levels of PAX-5 protein.
      • 组成:
      • The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
      • 来源:
      • Mouse, Monoclonal/IgG
      • 稀释:
      • Ready to use for IHC
      • 纯化工艺:
      • The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
      • 储存:
      • 2°C to 8°C/1 year
      • 其他名称:
      • Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP)
      • 功能:
      • developmental stage:Expressed at early B-cell differentiation, in the developing CNS and in adult testis.,disease:A chromosomal aberration involving PAX5 is a cause of acute lymphoblastic leukemia. Translocation t(9;18)(p13;q11.2) with ZNF521. Translocation t(9;3)(p13;p14.1) with FOXP1. Translocation t(9;12)(p13;p13) with ETV6.,function:May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.,PTM:O-glycosylated.,similarity:Contains 1 paired domain.,subunit:Interacts with DAXX (By similarity). Binds DNA as a monomer. Binds TLE4.,
      • 细胞定位:
      • Nuclear
      • 产品图片
      • Human tonsil tissue was stained with Anti-PAX-5 (PTR1332) Antibody
      • Mouse spleen tissue was stained with Anti-PAX-5 (PTR1332) Antibody
      • Rat spleen tissue was stained with Anti-PAX-5 (PTR1332) Antibody