- 靶点:
- MEK-4
- 基因名称:
- PAX5
- 蛋白名称:
- PAX-5
- Human Gene Id:
- 5079
- Human Swiss Prot No:
- Q02548
- Mouse Gene Id:
- 18507
- Mouse Swiss Prot No:
- Q02650
- 免疫原:
- Synthesized peptide derived from human PAX-5 AA range:300-383
- 特异性:
- This antibody detects endogenous levels of PAX-5 protein.
- 组成:
- The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
- 来源:
- Mouse, Monoclonal/IgG
- 稀释:
- Ready to use for IHC
- 纯化工艺:
- The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
- 储存:
- 2°C to 8°C/1 year
- 其他名称:
- Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP)
- 功能:
- developmental stage:Expressed at early B-cell differentiation, in the developing CNS and in adult testis.,disease:A chromosomal aberration involving PAX5 is a cause of acute lymphoblastic leukemia. Translocation t(9;18)(p13;q11.2) with ZNF521. Translocation t(9;3)(p13;p14.1) with FOXP1. Translocation t(9;12)(p13;p13) with ETV6.,function:May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.,PTM:O-glycosylated.,similarity:Contains 1 paired domain.,subunit:Interacts with DAXX (By similarity). Binds DNA as a monomer. Binds TLE4.,
- 细胞定位:
- Nuclear
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- Antibody-FAQs
- 产品图片
- Human tonsil tissue was stained with Anti-PAX-5 (PTR1332) Antibody
- Mouse spleen tissue was stained with Anti-PAX-5 (PTR1332) Antibody
- Rat spleen tissue was stained with Anti-PAX-5 (PTR1332) Antibody