PAX-5 (PTR1332) mouse mAb
- 货号:YM6693
- 应用:IHC;ELISA
- 种属:Human;Mouse;Rat;
- 免疫原:
- Synthesized peptide derived from human PAX-5 AA range:300-383
- 特异性:
- This antibody detects endogenous levels of PAX-5 protein.
- 组成:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- 来源:
- Mouse, Monoclonal/IgG
- 稀释:
- IHC 1:200-400. ELISA 1:500-5000
- 纯化工艺:
- The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP)
- 功能:
- developmental stage:Expressed at early B-cell differentiation, in the developing CNS and in adult testis.,disease:A chromosomal aberration involving PAX5 is a cause of acute lymphoblastic leukemia. Translocation t(9;18)(p13;q11.2) with ZNF521. Translocation t(9;3)(p13;p14.1) with FOXP1. Translocation t(9;12)(p13;p13) with ETV6.,function:May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.,PTM:O-glycosylated.,similarity:Contains 1 paired domain.,subunit:Interacts with DAXX (By similarity). Binds DNA as a monomer. Binds TLE4.,
![](/uploadfiles/PIC/PTR1332-Tonsil.jpg)
- Human tonsil tissue was stained with Anti-PAX-5 (PTR1332) Antibody
![](/uploadfiles/PIC/PTR1332-mouse-spleen.jpg)
- Mouse spleen tissue was stained with Anti-PAX-5 (PTR1332) Antibody
![](/uploadfiles/PIC/PTR1332-rat-spleen.jpg)
- Rat spleen tissue was stained with Anti-PAX-5 (PTR1332) Antibody