CA IX (PTR2373) mouse mAb
- 货号:YM6225
- 应用:IHC;ELISA
- 种属:Human;
- 简介:
- >>Nitrogen metabolism;>>Metabolic pathways
- 蛋白名称:
- Carbonic anhydrase 9
- 特异性:
- This antibody detects endogenous levels of CA IX protein.
- 组成:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- 来源:
- Mouse, Monoclonal/IgG
- 稀释:
- IHC 1:200-400. ELISA 1:500-5000
- 纯化工艺:
- The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- G250; MN; Carbonic anhydrase 9; Carbonate dehydratase IX; Carbonic anhydrase IX; CA-IX; CAIX; Membrane antigen MN; P54/58N; Renal cell carcinoma-associated antigen G250; RCC-associated antigen G250; pMW1
- 功能:
- catalytic activity:H(2)CO(3) = CO(2) + H(2)O.,cofactor:Zinc.,function:Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.,induction:By hypoxia.,PTM:Asn-346 bears high-mannose type glycan structures.,similarity:Belongs to the alpha-carbonic anhydrase family.,subcellular location:Found on the surface microvilli and in the nucleus, particularly in nucleolus.,subunit:Forms oligomers linked by disulfide bonds.,tissue specificity:Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.,
- 组织表达:
- Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.
![](/uploadfiles/PIC/PTR2373-Stomach.jpg)
- Human stomach tissue was stained with Anti-CA IX (PTR2373) Antibody
![](/uploadfiles/PIC/PTR2373-colon-carcinoma(1).jpg)
- Human colon carcinoma tissue was stained with Anti-CA IX (PTR2373) Antibody
![](/uploadfiles/PIC/PTR2373-colon-carcinoma(2).jpg)
- Human colon carcinoma tissue was stained with Anti-CA IX (PTR2373) Antibody
![](/uploadfiles/PIC/PTR2373-renal-clear-cell-carcinoma(1).jpg)
- Human renal clear cell carcinoma tissue was stained with Anti-CA IX (PTR2373) Antibody
![](/uploadfiles/PIC/PTR2373-renal-clear-cell-carcinoma(2).jpg)
- Human renal clear cell carcinoma tissue was stained with Anti-CA IX (PTR2373) Antibody