• 靶点：
• KSP-Cadherin

• 基因名称：
• CDH16 UNQ695/PRO1340

• 蛋白名称：
• KSP-Cadherin

• Human Gene Id：
• 1014

• Human Swiss Prot No：
• O75309

• 免疫原：
• Synthesized peptide derived from human KSP-Cadherin AA range: 700-829

• 特异性：
• The antibody can specifically recognize human KSP-Cadherin protein, and has no cross reaction with E-cadherin, N-cadherin, P-cadherin.

• 组成：
• The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300

• 来源：
• Mouse, Monoclonal/IgG1, kappa

• 稀释：
• Ready to use for IHC

• 纯化工艺：
• The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

• 储存：
• 2°C to 8°C/1 year

• 其他名称：
• Cadherin-16 (Kidney-specific cadherin;Ksp-cadherin)

• 背景：
• This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011],

• 功能：
• function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 6 cadherin domains.,tissue specificity:Kidney specific.,

• 细胞定位：
• Cytoplasmic, Membranous

• 组织表达：
• Kidney specific.

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