TRAP (ABT239) mouse mAb (Ready to Use)
- 货号:YM6106R
- 应用:IHC
- 种属:Human;
- 简介:
- >>Riboflavin metabolism;>>Metabolic pathways;>>Lysosome;>>Osteoclast differentiation;>>Rheumatoid arthritis
- 蛋白名称:
- Type 5 acid phosphatase;Acid phosphatase 5 tartrate resistant;Acid phosphatase 5, tartrate resistant;ACP5;EC 3.1.3.2;MGC117378;PPA5_HUMAN;serum band 5 tartrate-resistant acid phosphatase;SPENCDI;T5ap;
- 免疫原:
- Synthesized peptide derived from human TRAP AA range: 250-325
- 特异性:
- The antibody can specifically recognize human TRAP protein.
- 组成:
- The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
- 来源:
- Mouse, Monoclonal/IgG2a, kappa
- 纯化工艺:
- The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
- 其他名称:
- Type 5 acid phosphatase;Acid phosphatase 5 tartrate resistant;Acid phosphatase 5, tartrate resistant;ACP5;EC 3.1.3.2;MGC117378;PPA5_HUMAN;serum band 5 tartrate-resistant acid phosphatase;SPENCDI;T5ap;Tartrate resistant acid ATPase;Tartrate resistant acid phosphatase type 5;Tartrate resistant acid phosphatase type 5 precursor;Tartrate-resistant acid ATPase;Tartrate-resistant acid phosphatase type 5;TR AP;TR-AP;TRACP 5;TRAP;TrATPase;Type 5 acid phosphatase
- 背景:
- This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. [provided by RefSeq, Aug 2008],
- 功能:
- catalytic activity:A phosphate monoester + H(2)O = an alcohol + phosphate.,cofactor:Binds 2 iron ions per subunit.,disease:This relatively minor intracellular isozyme of acid phosphatase can become the dominant isozyme in certain pathological states (Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias).,similarity:Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.,subunit:Exists either as monomer or, after proteolytic processing, as a dimer of two chains linked by disulfide bond(s).,
![](/uploadfiles/PIC/V0467-giant-cell-tumor.jpg)
- Human giant cell tumor tissue was stained with Anti-TRAP (ABT239) Antibody
![](/uploadfiles/PIC/V0467-lung.jpg)
- Human lung tissue was stained with Anti-TRAP (ABT239) Antibody