Synaptophysin (ABT533) mouse mAb (Ready to Use)
- 货号:YM6105R
- 应用:IHC
- 种属:Human;Mouse;Rat;Bovin;
- 靶点:
- Synaptophysin
- 基因名称:
- SYP
- 蛋白名称:
- Major synaptic vesicle protein p38;MRX96;MRXSYP;Syn p38;Synaptophysin;Syp;SYPH;SYPH_HUMAN;SypI
- Human Swiss Prot No:
- P08247
- Mouse Swiss Prot No:
- Q62277
- Rat Swiss Prot No:
- P07825
- 免疫原:
- Synthesized peptide derived from human Synaptophysin AA range: 200-313
- 特异性:
- The antibody can specifically recognize human Synaptophysin protein.
- 组成:
- The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
- 来源:
- Mouse, Monoclonal/IgG1, kappa
- 稀释:
- Ready to use for IHC
- 纯化工艺:
- The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
- 储存:
- 2°C to 8°C/1 year
- 其他名称:
- Major synaptic vesicle protein p38;MRX96;MRXSYP;Syn p38;Synaptophysin;Syp;SYPH;SYPH_HUMAN;SypI
- 背景:
- This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR). [provided by RefSeq, Aug 2011],
- 功能:
- domain:The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein.,function:Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane.,online information:Synaptophysin entry,PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the synaptophysin/synaptobrevin family.,similarity:Contains 1 MARVEL domain.,subunit:Homohexamer or homotetramer.,tissue specificity:Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.,
- 细胞定位:
- Cytoplasmic
- 组织表达:
- Pancreas/ Colon
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- 产品图片
- Human adrenal gland tissue was stained with Anti-Synaptophysin (ABT533) Antibody
- Human pancreas tissue was stained with Anti-Synaptophysin (ABT533) Antibody
- Human pancreas tissue was stained with Anti-Synaptophysin (ABT533) Antibody