• 靶点：
• RRAD

• 基因名称：
• RRAD RAD

• 蛋白名称：
• GTP-binding protein RAD (RAD1) (Ras associated with diabetes)

• Human Gene Id：
• 6236

• Human Swiss Prot No：
• P55042

• Mouse Gene Id：
• 0

• Mouse Swiss Prot No：
• O88667

• 免疫原：
• Synthesized peptide derived from human protein. AA range: 1-100

• 特异性：
• This antibody detects endogenous levels of RRAD at Human

• 组成：
• Liquid in PBS containing 50% glycerol, and 0.05% proclin 300.

• 来源：
• Monoclonal, Mouse IgG1,Kappa

• 稀释：
• WB 1:500-2000,ELISA 1:5000-20000

• 纯化工艺：
• The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• GTP-binding protein RAD (RAD1) (Ras associated with diabetes)

• 实测条带：
• 33kD

• 功能：
• May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.

• 细胞定位：
• Cell membrane .

• 组织表达：
• Most abundantly expressed in the heart. Also found in the skeletal muscle and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans.

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