GLUT-1 (PTR2138) mouse mAb
- 货号：YM4463
- 应用：WB;IF;ELISA
- 种属：Human;Mouse;Rat;
- 蛋白名称：
- Solute carrier family 2, facilitated glucose transporter member 1 (Glucose transporter type 1, erythrocyte/brain) (GLUT-1) (HepG2 glucose transporter)
- 免疫原：
- Synthesized peptide derived from human GLUT-1 AA range: 400-492
- 特异性：
- This antibody detects endogenous levels of GLUT-1 protein.
- 组成：
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- 来源：
- Mouse, Monoclonal/IgG
- 稀释：
- WB 1:500-2000. IF 1:100-500. ELISA 1:1000-5000
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 背景：
- solute carrier family 2 member 1(SLC2A1) Homo sapiens This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia. [provided by RefSeq, Apr 2013],
- 功能：
- Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake . Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses . Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain . In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors (By similarity).
- 组织表达：
- Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues.
- Whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-GLUT-1 (PTR2138) antibody. The HRP-conjugated Goat anti-Mouse IgG(H + L) antibody was used to detect the antibody.
Lane 1: HepG2
