CD80 (PTR1386) recombinant mouse mAb
- 货号：YM4238
- 应用：FCM;ELISA
- 种属：Human
- 简介：
- >>Cell adhesion molecules;>>Toll-like receptor signaling pathway;>>Intestinal immune network for IgA production;>>Type I diabetes mellitus;>>Autoimmune thyroid disease;>>Systemic lupus erythematosus;>>Rheumatoid arthritis;>>Allograft rejection;>>Graft-versus-host disease;>>Viral myocarditis
- 基因名称：
- CD80 CD28LG CD28LG1 LAB7
- 蛋白名称：
- T-lymphocyte activation antigen CD80 (Activation B7-1 antigen) (BB1) (CTLA-4 counter-receptor B7.1) (B7) (CD antigen CD80)
- 免疫原：
- Purified recombinant human CD80
- 特异性：
- This recombinant monoclonal antibody can detects endogenous levels of CD80 protein.
- 组成：
- Phosphate-buffered solution
- 来源：
- Monoclonal,Mouse,IgG1,kappa
- 稀释：
- ELISA 1:5000-100000;FCM 1-2μg/Test
- 纯化工艺：
- Recombinant Expression and Affinity purified
- 浓度：
- Please check the information on the tube
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- T-lymphocyte activation antigen CD80 (Activation B7-1 antigen;BB1;CTLA-4 counter-receptor B7.1;B7;CD antigen CD80)
- 背景：
- The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011],
- 功能：
- function:Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.,tissue specificity:Expressed on activated B-cells, macrophages and dendritic cells.,
- 细胞定位：
- Membrane; Single-pass type I membrane protein.
- 组织表达：
- Expressed on activated B-cells, macrophages and dendritic cells.
