4E-BP2 mouse mAb

    • 货号：YM1454
    • 应用：WB
    • 种属：Transfected
      • 靶点：
      • 4E-BP2
      • 简介：
      • >>Longevity regulating pathway - multiple species
      • 基因名称：
      • eif4ebp2
      • Human Gene Id：
      • 1979
      • Human Swiss Prot No：
      • Q13542
      • Mouse Swiss Prot No：
      • P70445
      • 免疫原：
      • Recombinant protein of human 4E-BP2.
      • 特异性：
      • Transfected Only.
      • 组成：
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源：
      • Monoclonal, Mouse
      • 稀释：
      • wb dilution 1:1000
      • 纯化工艺：
      • The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
      • 浓度：
      • 1 mg/ml
      • 储存：
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称：
      • 4E-BP2；4EBP2；4EBP2_HUMAN；eIF4E binding protein 2；eIF4E-binding protein 2；Eif4ebp2；Eukaryotic translation initiation factor 4E binding protein 1；Eukaryotic translation initiation factor 4E-binding protein 2；PHASII；phosphorylated, heat and acid stable regulated by insulin protein II.
      • 实测条带：
      • 15-20kD
      • 背景：
      • eukaryotic translation initiation factor 4E binding protein 2(EIF4EBP2) Homo sapiens This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008],
      • 功能：
      • function:Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase pathway.,PTM:Phosphorylated on serine and threonine residues in response to insulin, EGF and PDGF.,similarity:Belongs to the eIF4E-binding protein family.,subunit:Nonphosphorylated EIF4EBP2 interacts with EIF4E.,
      • 细胞定位：
      • intracellular,cytoplasm,
      • 组织表达：
      • Lung,Placenta,Uterus,
      • 产品图片
      • Western blot detection of 4E-BP2 in CHO-K1 cell lysate(A)and CHO-K1 transfected by EGFP-4E-BP2 (B)cell lysate using 4E-BP2 mouse mAb (1:1000 diluted).

      相关报价

      • 货号：
      • YM1454
      • 规格：
      • 40μL / 100μL / 200μL
      • 价格：
      • ¥960 / 2300 / 3780
      • 货期：
      • 预计发货时间为
        2024-12-01
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