Rab 2A Monoclonal Antibody
- 货号:YM1089
- 应用:WB;IF
- 种属:Human;Mouse;Rat;Bovine;Chicken;Dog;Pig;Zebrafish
- 靶点:
- Rab 2A
- 简介:
- >>AMPK signaling pathway
- 基因名称:
- RAB2A
- 蛋白名称:
- Ras-related protein Rab-2A
- Human Gene Id:
- 5862
- Human Swiss Prot No:
- P61019
- Mouse Gene Id:
- 59021
- Mouse Swiss Prot No:
- P53994
- Rat Gene Id:
- 65158
- Rat Swiss Prot No:
- P05712
- 免疫原:
- Purified recombinant human Rab 2A (C-terminus) protein fragments expressed in E.coli.
- 特异性:
- Rab 2A Monoclonal Antibody detects endogenous levels of Rab 2A protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Monoclonal, Mouse
- 稀释:
- WB 1:1000 - 1:2000. IF 1:100 - 1:500. Not yet tested in other applications.
- 纯化工艺:
- Affinity purification
- 浓度:
- 1 mg/ml
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- RAB2A;RAB2;Ras-related protein Rab-2A
- 分子量:
- 24kD
- 背景:
- The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
- 功能:
- function:Required for protein transport from the endoplasmic reticulum to the Golgi complex.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Interacts with PRKCI.,
- 细胞定位:
- Endoplasmic reticulum-Golgi intermediate compartment membrane ; Lipid-anchor . Melanosome . Endoplasmic reticulum membrane ; Lipid-anchor . Golgi apparatus membrane ; Lipid-anchor . Cytoplasmic vesicle, secretory vesicle, acrosome . Localized in the Golgi apparatus in the round spermatids and in the acrosome in the elongating spermatid (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). .
- 组织表达:
- Brain,Skin,
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- Antibody-FAQs
- 产品图片
- Western Blot analysis using Rab 2A Monoclonal Antibody against HeLa cell lysate.
- Immunofluorescence analysis of HeLa cells using Rab 2A Monoclonal Antibody.