GATA-5 Monoclonal Antibody
- 货号:YM0300
- 应用:WB;ELISA
- 种属:Human
- 蛋白名称:
- Transcription factor GATA-5
- 免疫原:
- Purified recombinant fragment of human GATA-5 expressed in E. Coli.
- 特异性:
- GATA-5 Monoclonal Antibody detects endogenous levels of GATA-5 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 稀释:
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
- 纯化工艺:
- Affinity purification
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- GATA5;Transcription factor GATA-5;GATA-binding factor 5
- 背景:
- The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. [provided by RefSeq, Jul 2008],
- 功能:
- function:Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer. May play an important role in the transcriptional program(s) that underlies smooth muscle cell diversity.,similarity:Contains 2 GATA-type zinc fingers.,
- Western Blot analysis using GATA-5 Monoclonal Antibody against HEK293 (1) and GATA5-hIgGFc transfected HEK293 (2) cell lysate.