• 靶点：
• Dkk-3

• 基因名称：
• DKK3

• 蛋白名称：
• Dickkopf-related protein 3

• Human Gene Id：
• 27122

• Human Swiss Prot No：
• Q9UBP4

• Mouse Swiss Prot No：
• Q9QUN9

• 免疫原：
• Purified recombinant fragment of human Dkk-3 expressed in E. Coli.

• 特异性：
• Dkk-3 Monoclonal Antibody detects endogenous levels of Dkk-3 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Monoclonal, Mouse

• 稀释：
• WB 1:500 - 1:2000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.

• 纯化工艺：
• Affinity purification

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• DKK3;REIC;Dickkopf-related protein 3;Dickkopf-3;Dkk-3;hDkk-3

• 分子量：
• 38kD

• 背景：
• This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],

• 功能：
• function:Inhibitor of Wnt signaling pathway .,PTM:N-glycosylated.,similarity:Belongs to the dickkopf family.,tissue specificity:Highest expression in heart, brain, and spinal cord.,

• 细胞定位：
• Secreted.

• 组织表达：
• Highest expression in heart, brain, and spinal cord.

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