c-Myb (Acetyl Lys480) rabbit pAb

  • 货号:YK0158
  • 应用:WB;ELISA
  • 种属:Human;Mouse
    • 靶点:
    • c-Myb
    • 简介:
    • >>PI3K-Akt signaling pathway
    • 基因名称:
    • MYB
    • 蛋白名称:
    • c-Myb (Acetyl Lys480)
    • Human Gene Id:
    • 4602
    • Human Swiss Prot No:
    • P10242
    • Mouse Swiss Prot No:
    • P06876
    • 免疫原:
    • Synthesized peptide derived from human c-Myb (Acetyl Lys480)
    • 特异性:
    • This antibody detects endogenous levels of Human,Mouse c-Myb (Acetyl Lys480)
    • 组成:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • 来源:
    • Polyclonal, Rabbit,IgG
    • 稀释:
    • WB 1:1000-2000 ELISA 1:5000-20000
    • 纯化工艺:
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • 浓度:
    • 1 mg/ml
    • 储存:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 其他名称:
    • Transcriptional activator Myb (Proto-oncogene c-Myb)
    • 实测条带:
    • 70kD
    • 背景:
    • domain:Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression.,function:Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.,PTM:Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.,PTM:Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Binds MYBBP1A. Interacts with HIPK2, MAF and NLK.,
    • 功能:
    • transcription, regulation of transcription, DNA-dependent, regulation of transcription, regulation of RNA metabolic process,
    • 细胞定位:
    • Nucleus .