c-Myb (Acetyl Lys471) rabbit pAb
- 货号:YK0157
- 应用:WB;ELISA
- 种属:Human;Mouse
- 简介:
- >>PI3K-Akt signaling pathway
- 蛋白名称:
- c-Myb (Acetyl Lys471)
- 免疫原:
- Synthesized peptide derived from human c-Myb (Acetyl Lys471)
- 特异性:
- This antibody detects endogenous levels of Human,Mouse c-Myb (Acetyl Lys471)
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:1000-2000 ELISA 1:5000-20000
- 纯化工艺:
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- Transcriptional activator Myb (Proto-oncogene c-Myb)
- 背景:
- domain:Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression.,function:Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.,PTM:Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.,PTM:Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Binds MYBBP1A. Interacts with HIPK2, MAF and NLK.,
- 功能:
- transcription, regulation of transcription, DNA-dependent, regulation of transcription, regulation of RNA metabolic process,