IL-2 rabbit-FC recombinant protein

  • 货号:YD3110
  • 种属:Human;
    • 纯度:
    • >90% as determined by SDS-PAGE
    • 基因名称:
    • IL-2
    • 蛋白名称:
    • Interleukin-2
    • 序列:
    • Amino acid:21-153,with rabbit FC tag.
    • Human Gene Id:
    • 3558
    • Human Swiss Prot No:
    • P60568
    • 组成:
    • Phosphate-buffered solution
    • 来源:
    • Mammalian cells
    • 储存:
    • -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
    • 其他名称:
    • IL2;Interleukin-2;IL-2;T-cell growth factor;TCGF;Aldesleukin
    • 背景:
    • The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008],
    • 功能:
    • disease:A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.,function:Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.,online information:Interleukin-2 entry,online information:The Singapore human mutation and polymorphism database,pharmaceutical:Available under the name Proleukin (Chiron). Used in patients with renal cell carcinoma or metastatic melanoma.,similarity:Belongs to the IL-2 family.,
    • 细胞定位:
    • Secreted.
    • 组织表达:
    • Blood,PCR rescued clones,Placenta,Spleen,