CD39-FC recombinant protein

  • 货号:YD3019
  • 种属:Human;
    • 纯度:
    • >90% as determined by SDS-PAGE
    • 基因名称:
    • ENTPD1
    • 蛋白名称:
    • Ectonucleoside triphosphate diphosphohydrolase 1 (EC 3.6.1.5) (ATP diphosphohydrolase) (ATP-DPH) (ATPDase) (Ecto-ATP diphosphohydrolase 1) (Ecto-ATPDase 1) (Ecto-ATPase 1) (Ecto-apyrase) (Lymphoid cel
    • 序列:
    • Amino acid:38-478,with FC tag.
    • Human Gene Id:
    • 953
    • Human Swiss Prot No:
    • P49961
    • 组成:
    • Phosphate-buffered solution
    • 来源:
    • Mammalian cells
    • 储存:
    • -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
    • 其他名称:
    • Ectonucleoside triphosphate diphosphohydrolase 1 ;EC 3.6.1.5;ATP diphosphohydrolase;ATP-DPH;ATPDase;Ecto-ATP diphosphohydrolase 1;Ecto-ATPDase 1;Ecto-ATPase 1;Ecto-apyrase;Lymphoid cell activation antigen;Nucleoside triphosphate diphosphohydrolase 1;NTPDase1;CD antigen CD39;ENTPD1;CD39;
    • 功能:
    • Catalyzes the hydrolysis of both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs) in two distinct successive phosphate-releasing steps, with NDPs as intermediates and participates in the regulation of extracellular levels of nucleotides (Probable) (PubMed:8529670, PubMed:8626624, PubMed:8955160, PubMed:8996251). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow (PubMed:8955160, PubMed:8996251).
    • 细胞定位:
    • Membrane ; Multi-pass membrane protein . Membrane, caveola .
    • 组织表达:
    • Expressed primarily on activated lymphoid cells (PubMed:7930580). Also expressed in endothelial tissues (PubMed:8955160). Highly expressed in placenta, lung, skeletal muscle, kidney (PubMed:8955160).