CD226 (DNAM-1)-FC recombinant protein

  • 货号:YD3011
  • 种属:Human;
    • 纯度:
    • >90% as determined by SDS-PAGE
    • 基因名称:
    • CD226
    • 蛋白名称:
    • CD226 antigen (DNAX accessory molecule 1) (DNAM-1) (CD antigen CD226)
    • 序列:
    • Amino acid:19-254,with FC tag.
    • Human Swiss Prot No:
    • Q15762
    • 组成:
    • Phosphate-buffered solution
    • 来源:
    • Mammalian cells
    • 储存:
    • -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
    • 其他名称:
    • CD226 antigen ;DNAX accessory molecule 1;DNAM-1;CD antigen CD226;CD226;DNAM1;
    • 功能:
    • Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell (PubMed:8673704). Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding (PubMed:26755705).
    • 细胞定位:
    • Cell membrane ; Single-pass type I membrane protein .
    • 组织表达:
    • Expressed by peripheral blood T-lymphocytes.