CD226 (DNAM-1)-FC recombinant protein
- 纯度:
- >90% as determined by SDS-PAGE
- 蛋白名称:
- CD226 antigen (DNAX accessory molecule 1) (DNAM-1) (CD antigen CD226)
- 序列:
- Amino acid:19-254,with FC tag.
- 组成:
- Phosphate-buffered solution
- 储存:
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- 其他名称:
- CD226 antigen ;DNAX accessory molecule 1;DNAM-1;CD antigen CD226;CD226;DNAM1;
- 功能:
- Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell (PubMed:8673704). Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding (PubMed:26755705).
- 细胞定位:
- Cell membrane ; Single-pass type I membrane protein .
- 组织表达:
- Expressed by peripheral blood T-lymphocytes.