KLRG1 (MAFA)-FC recombinant protein

  • 货号:YD3004
  • 种属:Human;
    • 纯度:
    • >90% as determined by SDS-PAGE
    • 基因名称:
    • KLRG1
    • 蛋白名称:
    • Killer cell lectin-like receptor subfamily G member 1 (C-type lectin domain family 15 member A) (ITIM-containing receptor MAFA-L) (MAFA-like receptor) (Mast cell function-associated antigen)
    • 序列:
    • Amino acid:60-195,with FC tag.
    • Human Swiss Prot No:
    • Q96E93
    • 组成:
    • Phosphate-buffered solution
    • 来源:
    • Mammalian cells
    • 储存:
    • -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
    • 其他名称:
    • Killer cell lectin-like receptor subfamily G member 1 ;C-type lectin domain family 15 member A;ITIM-containing receptor MAFA-L;MAFA-like receptor;Mast cell function-associated antigen;KLRG1;CLEC15A;MAFA;MAFAL;
    • 功能:
    • Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
    • 细胞定位:
    • Cell membrane ; Single-pass type II membrane protein .
    • 组织表达:
    • Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells.