CD88 (C5aR)-FC recombinant protein
- 纯度：
- >90% as determined by SDS-PAGE
- 蛋白名称：
- C5a anaphylatoxin chemotactic receptor 1 (C5a anaphylatoxin chemotactic receptor) (C5a-R) (C5aR) (CD antigen CD88)
- 序列：
- Amino acid:1-37,with FC tag.
- 组成：
- Phosphate-buffered solution
- 储存：
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- 其他名称：
- C5a anaphylatoxin chemotactic receptor 1 ;C5a anaphylatoxin chemotactic receptor;C5a-R;C5aR;CD antigen CD88;C5AR1;C5AR;C5R1;
- 功能：
- Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:10636859, PubMed:15153520, PubMed:1847994, PubMed:29300009, PubMed:7622471, PubMed:8182049, PubMed:9553099). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:7622471, PubMed:8182049, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
- 细胞定位：
- Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle . Note=Phosphorylated C5aR colocalizes with ARRB1 and ARRB2 in cytoplasmic vesicles. .
