Recombinant Human ACE2 protein
- 货号：YD2195
- 应用：ELISA ECL Immunogold
- 种属：Human
- 纯度：
- >90% as determined by SDS-PAGE
- 简介：
- For research use only .Not for use in clinical diagnostic procedures.
- 蛋白名称：
- ACE-related carboxypeptidase
Angiotensin-converting enzyme homolog
Metalloprotease MPROT15
- 浓度：
- >90% as determined by SDS-PAGE
- 储存：
- Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
- 背景：
- Recombinant Human ACE2 is produced by Mammalian cells expression system and the target gene encoding Met1-Ser740 is expressed with C-HisTag
- 功能：
- Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
