Recombinant SARS-CoV-2(Covid-19) NSP10

  • 货号:YD2188
  • 应用:ELISA ECL Immunogold
  • 种属:Human virus
    • 纯度:
    • >90% as determined by SDS-PAGE
    • 简介:
    • For research use only .Not for use in clinical diagnostic procedures.
    • 基因名称:
    • ORF1ab
    • 蛋白名称:
    • nsp10,GFL
    • 来源:
    • E.coli
    • 稀释:
    • Testing in progress
    • 浓度:
    • >90% as determined by SDS-PAGE
    • 储存:
    • Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week . Store at -20 to -80 °C for twelve months from the date of receipt.
    • 分子量:
    • 17.99kDa
    • 实测条带:
    • 18kDa
    • 背景:
    • Recombinant SARS-CoV-2 NSP10 is produced by E.coli expression system and the target gene encoding Ala1-Gln139 is expressed with N-His Tag
    • 功能:
    • Nsp10 have shown that it is a 15-kDa protein of unknown function that has been shown to interact with itself, nsp1, and nsp7. It colocalizes with N to sites of viral replication and is essential for replication. It plays a pivotal role in viral transcription by stimulating both nsp14 3'-5' exoribonuclease and nsp16 2'-O-methyltransferase activities. Therefore plays an essential role in viral mRNAs cap methylation. Nsp10 is a critical regulator of coronavirus RNA synthesis and may play an important role in polyprotein processing.