• 基因名称：
• NRF1

• 蛋白名称：
• Nrf1 protein

• 序列：
• Amino acid: 40-279, with his-MBP tag.

• Human Gene Id：
• 4899

• Human Swiss Prot No：
• Q16656

• Mouse Swiss Prot No：
• Q9WU00

• 组成：
• Liquid in PBS

• 来源：
• E.coli

• 稀释：
• WB 1:500-2000

• 浓度：
• SDS-PAGE >90%

• 储存：
• -20°C/6 month,-80°C for long storage

• 其他名称：
• Nuclear respiratory factor 1 (NRF-1) (Alpha palindromic-binding protein) (Alpha-pal)

• 背景：
• function:Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.,PTM:Phosphorylation enhances DNA binding.,similarity:Belongs to the NRF1/Ewg family.,subunit:Homodimer. Binds DNA as a dimer. Interacts with PPRC1.,tissue specificity:Ubiquitously expressed with strongest expression in skeletal muscle.,

• 功能：
• generation of precursor metabolites and energy, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, mitochondrion organization, regulation of transcription, regulation of RNA metabolic process,

• 细胞定位：
• Nucleus.

• 组织表达：
• Ubiquitously expressed with strongest expression in skeletal muscle.

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