• 基因名称：
• CANX

• 蛋白名称：
• Calnexin protein

• 序列：
• Amino acid: 19-236, with his-MBP tag.

• Human Gene Id：
• 821

• Human Swiss Prot No：
• P27824

• Mouse Swiss Prot No：
• P35564

• 组成：
• Liquid in PBS

• 来源：
• E.coli

• 稀释：
• WB 1:500-2000

• 浓度：
• SDS-PAGE >90%

• 储存：
• -20°C/6 month,-80°C for long storage

• 其他名称：
• Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)

• 背景：
• function:Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.,online information:Calnexin entry,similarity:Belongs to the calreticulin family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,

• 功能：
• protein folding, protein localization, protein secretion, protein transport, secretion by cell, establishment of protein localization, secretion,

• 细胞定位：
• Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endoplasmic reticulum . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065). The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232). .

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