HSC70 protein

    • 货号：YD0039
    • 应用：WB;SDS-PAGE
    • 种属：Human
      • 基因名称：
      • HSPA8
      • 蛋白名称：
      • HSC70 protein
      • 序列：
      • Amino acid: 222-369, with his-MBP tag.
      • Human Gene Id：
      • 3312
      • Human Swiss Prot No：
      • P11142
      • Mouse Swiss Prot No：
      • P63017
      • 组成：
      • Liquid in PBS
      • 来源：
      • E.coli
      • 稀释：
      • WB 1:500-2000
      • 浓度：
      • SDS-PAGE >90%
      • 储存：
      • -20°C/6 month,-80°C for long storage
      • 其他名称：
      • Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8)
      • 背景：
      • function:Chaperone. Isoform 2 may function as an endogenous inhibitory regulator of HSC70 by competing the co-chaperones.,induction:Constitutively synthesized.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the heat shock protein 70 family.,subcellular location:Translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Interacts with HSPH1/HSP105. Interacts with IRAK1BP1 (By similarity). Interacts with PACRG and TSC2. Interacts with SV40 VP1.,tissue specificity:Ubiquitous.,
      • 功能：
      • protein folding, 'de novo' protein folding, post-Golgi vesicle-mediated transport, response to unfolded protein,response to organic substance, membrane organization, vesicle-mediated transport, intracellular transport, Golgi vesicle transport, 'de novo' posttranslational protein folding, chaperone mediated protein folding requiring cofactor,regulation of cell cycle, response to protein stimulus,
      • 细胞定位：
      • Cytoplasm. Melanosome. Nucleus, nucleolus. Cell membrane. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock.
      • 组织表达：
      • Ubiquitous.
      • 产品图片

      相关报价

      • 货号：
      • YD0039
      • 规格：
      • 100μg
      • 价格：
      • ¥2300
      • 货期：
      • 预计发货时间为
        2024-12-29
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