ERK3 protein

    • 货号:YD0029
    • 应用:WB;SDS-PAGE
    • 种属:Human
      • 基因名称:
      • MAPK6
      • 蛋白名称:
      • ERK3 protein
      • 序列:
      • Amino acid: 299-526, with his-MBP tag.
      • Human Gene Id:
      • 5597
      • Human Swiss Prot No:
      • Q16659
      • Mouse Swiss Prot No:
      • Q61532
      • 组成:
      • Liquid in PBS
      • 来源:
      • E.coli
      • 稀释:
      • WB 1:500-2000
      • 浓度:
      • SDS-PAGE >90%
      • 储存:
      • -20°C/6 month,-80°C for long storage
      • 其他名称:
      • Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK)
      • 背景:
      • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,domain:The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.,enzyme regulation:Activated by threonine and tyrosine phosphorylation.,function:Phosphorylates microtubule-associated protein 2 (MAP2). May promote entry in the cell cycle.,PTM:Dually phosphorylated on Thr-626 and Tyr-628, which activates the enzyme.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.,
      • 功能:
      • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell cycle,phosphorylation,
      • 细胞定位:
      • Cytoplasm . Nucleus . Translocates to the cytoplasm following interaction with MAPKAPK5. .
      • 组织表达:
      • Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.
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