• 靶点：
• NOTCH3

• 简介：
• >>Endocrine resistance;>>Notch signaling pathway;>>Apelin signaling pathway;>>Th1 and Th2 cell differentiation;>>Thyroid hormone signaling pathway;>>Human papillomavirus infection;>>Pathways in cancer;>>MicroRNAs in cancer;>>Breast cancer

• 基因名称：
• NOTCH3

• 蛋白名称：
• NOTCH3 (Cleaved-Val1662)

• Human Gene Id：
• 4854

• Human Swiss Prot No：
• Q9UM47

• Mouse Gene Id：
• 18131

• Mouse Swiss Prot No：
• Q61982

• Rat Gene Id：
• 56761

• Rat Swiss Prot No：
• Q9R172

• 免疫原：
• Synthesized peptide derived from human NOTCH3 (Cleaved-Val1662)

• 特异性：
• This antibody detects endogenous levels of Human,Mouse,Rat NOTCH3 (Cleaved-Val1662, protein was cleaved amino acid sequence between 1661-1662 )

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:1000-2000 ELISA 1:5000-20000

• 纯化工艺：
• The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation;Notch 3 intracellular domain]

• 实测条带：
• 75 260kD

• 细胞定位：
• Cell membrane ; Single-pass type I membrane protein.; [Notch 3 intracellular domain]: Nucleus. Following proteolytical processing NICD is translocated to the nucleus.

• 组织表达：
• Ubiquitously expressed in fetal and adult tissues.

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