CD64 (PN0649) Nb-FC recombinant antibody

  • 货号:YA0651
  • 应用:FCM;ELISA
  • 种属:Human
    • 靶点:
    • CD64
    • 简介:
    • >>Phagosome;>>Osteoclast differentiation;>>Neutrophil extracellular trap formation;>>Hematopoietic cell lineage;>>Fc gamma R-mediated phagocytosis;>>Leishmaniasis;>>Staphylococcus aureus infection;>>Tuberculosis;>>Transcriptional misregulation in cancer;>>Acute myeloid leukemia;>>Systemic lupus erythematosus
    • 基因名称:
    • FCGR1A FCG1 FCGR1 IGFR1
    • 蛋白名称:
    • High affinity immunoglobulin gamma Fc receptor I (IgG Fc receptor I) (Fc-gamma RI) (FcRI) (Fc-gamma RIA) (FcgammaRIa) (CD antigen CD64)
    • Human Gene Id:
    • 2209
    • Human Swiss Prot No:
    • P12314
    • Mouse Swiss Prot No:
    • P26151
    • 免疫原:
    • Purified recombinant human CD64
    • 特异性:
    • This recombinant monoclonal antibody can detects endogenous levels of CD64 protein.
    • 组成:
    • Phosphate-buffered solution
    • 来源:
    • Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
    • 稀释:
    • ELISA 1:5000-100000;FCM 1-2μg/Test
    • 纯化工艺:
    • Recombinant Expression and Affinity purified
    • 浓度:
    • Please check the information on the tube
    • 储存:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 其他名称:
    • High affinity immunoglobulin gamma Fc receptor I (IgG Fc receptor I;Fc-gamma RI;FcRI;Fc-gamma RIA;FcgammaRIa;CD antigen CD64)
    • 实测条带:
    • 45kD
    • 背景:
    • This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008],
    • 功能:
    • function:High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.,online information:FCGR1A mutation db,PTM:N-glycosylated.,PTM:Phosphorylated on serine residues.,similarity:Belongs to the immunoglobulin superfamily. FCGR1 family.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subcellular location:Stabilized at the cell membrane through interaction with FCER1G.,subunit:Interacts with FCERG1; forms a functional signaling complex. Interacts with FLNA; prevents FCGR1A degradation. Interacts with EPB41L2, LAT and PPL.,tissue specificity:Monocyte/macrophage specific.,
    • 细胞定位:
    • Cell membrane ; Single-pass type I membrane protein . Stabilized at the cell membrane through interaction with FCER1G.
    • 组织表达:
    • Monocyte/macrophage specific.