CD64 (PN0649) Nb-FC recombinant antibody
- 货号：YA0651
- 应用：FCM;ELISA
- 种属：Human
- 简介：
- >>Phagosome;>>Osteoclast differentiation;>>Neutrophil extracellular trap formation;>>Hematopoietic cell lineage;>>Fc gamma R-mediated phagocytosis;>>Leishmaniasis;>>Staphylococcus aureus infection;>>Tuberculosis;>>Transcriptional misregulation in cancer;>>Acute myeloid leukemia;>>Systemic lupus erythematosus
- 基因名称：
- FCGR1A FCG1 FCGR1 IGFR1
- 蛋白名称：
- High affinity immunoglobulin gamma Fc receptor I (IgG Fc receptor I) (Fc-gamma RI) (FcRI) (Fc-gamma RIA) (FcgammaRIa) (CD antigen CD64)
- 免疫原：
- Purified recombinant human CD64
- 特异性：
- This recombinant monoclonal antibody can detects endogenous levels of CD64 protein.
- 组成：
- Phosphate-buffered solution
- 来源：
- Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
- 稀释：
- ELISA 1:5000-100000;FCM 1-2μg/Test
- 纯化工艺：
- Recombinant Expression and Affinity purified
- 浓度：
- Please check the information on the tube
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- High affinity immunoglobulin gamma Fc receptor I (IgG Fc receptor I;Fc-gamma RI;FcRI;Fc-gamma RIA;FcgammaRIa;CD antigen CD64)
- 背景：
- This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008],
- 功能：
- function:High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.,online information:FCGR1A mutation db,PTM:N-glycosylated.,PTM:Phosphorylated on serine residues.,similarity:Belongs to the immunoglobulin superfamily. FCGR1 family.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subcellular location:Stabilized at the cell membrane through interaction with FCER1G.,subunit:Interacts with FCERG1; forms a functional signaling complex. Interacts with FLNA; prevents FCGR1A degradation. Interacts with EPB41L2, LAT and PPL.,tissue specificity:Monocyte/macrophage specific.,
- 细胞定位：
- Cell membrane ; Single-pass type I membrane protein . Stabilized at the cell membrane through interaction with FCER1G.
- 组织表达：
- Monocyte/macrophage specific.
