IL-5 (PN0186) Nb-FC recombinant antibody
- 货号:YA0631
- 应用:ELISA
- 种属:Human
- 蛋白名称:
- Interleukin-5 (IL-5) (B-cell differentiation factor I) (Eosinophil differentiation factor) (T-cell replacing factor) (TRF)
- 免疫原:
- Purified recombinant Human IL-5
- 特异性:
- This recombinant monoclonal antibody can detects endogenous levels of IL-5 protein.
- 组成:
- Phosphate-buffered solution
- 来源:
- Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
- 纯化工艺:
- Recombinant Expression and Affinity purified
- 浓度:
- Please check the information on the tube
- 储存:
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- 其他名称:
- IL5;Interleukin-5;IL-5;B-cell differentiation factor I;Eosinophil differentiation factor;T-cell replacing factor;TRF;IL-5 nanobody;
- 背景:
- This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production ofThis cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases.This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF).This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 .This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]
- 功能:
- Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.,online information:Interleukin-5 entry,similarity:Belongs to the IL-5 family.,subunit:Homodimer; disulfide-linked.,