CD73 (PN0526) Nb-FC recombinant antibody

  • 货号:YA0502
  • 应用:ELISA;FCM
  • 种属:Human
    • 靶点:
    • CD73
    • 基因名称:
    • NT5E NT5 NTE
    • 蛋白名称:
    • 5'-nucleotidase (5'-NT) (EC 3.1.3.5) (Ecto-5'-nucleotidase) (CD antigen CD73)
    • Human Gene Id:
    • 4907
    • Human Swiss Prot No:
    • P21589
    • 免疫原:
    • Purified recombinant Human CD73
    • 特异性:
    • This recombinant monoclonal antibody can detects endogenous levels of CD73 protein.
    • 组成:
    • Phosphate-buffered solution
    • 来源:
    • Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
    • 稀释:
    • ELISA 1:5000-100000;FCM 1-2μg/Test
    • 纯化工艺:
    • Recombinant Expression and Affinity purified
    • 浓度:
    • Please check the information on the tube
    • 储存:
    • -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
    • 其他名称:
    • NT5E;NT5;NTE;5'-nucleotidase;5'-NT;Ecto-5'-nucleotidase;CD antigen CD73;CD73 nanobody;
    • 背景:
    • The protein encoded byThis gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects inThis gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found forThis gene.[provided by RefSeq, Mar 2011]
    • 功能:
    • catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Zinc.,disease:There is a decrease in the activity of NT5 in B-cell chronic lymphocytic leukemia.,Hydrolyzes extracellular nucleotides into membrane permeable nucleosides.,similarity:Belongs to the 5'-nucleotidase family.,subunit:Homodimer; disulfide-linked.,
    • 细胞定位:
    • Cell membrane ; Lipid-anchor, GPI-anchor .
    • 组织表达:
    • Leukocyte,Liver,Placenta,Skin