CD73 (PN0520) Nb-FC recombinant antibody
- 货号：YA0496
- 应用：ELISA
- 种属：Human
- 蛋白名称：
- 5'-nucleotidase (5'-NT) (EC 3.1.3.5) (Ecto-5'-nucleotidase) (CD antigen CD73)
- 免疫原：
- Purified recombinant Human CD73
- 特异性：
- This recombinant monoclonal antibody can detects endogenous levels of CD73 protein.
- 组成：
- Phosphate-buffered solution
- 来源：
- Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
- 纯化工艺：
- Recombinant Expression and Affinity purified
- 浓度：
- Please check the information on the tube
- 储存：
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- 其他名称：
- NT5E;NT5;NTE;5'-nucleotidase;5'-NT;Ecto-5'-nucleotidase;CD antigen CD73;CD73 nanobody;
- 背景：
- The protein encoded byThis gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects inThis gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found forThis gene.[provided by RefSeq, Mar 2011]
- 功能：
- catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Zinc.,disease:There is a decrease in the activity of NT5 in B-cell chronic lymphocytic leukemia.,Hydrolyzes extracellular nucleotides into membrane permeable nucleosides.,similarity:Belongs to the 5'-nucleotidase family.,subunit:Homodimer; disulfide-linked.,
- 细胞定位：
- Cell membrane ; Lipid-anchor, GPI-anchor .
- 组织表达：
- Leukocyte,Liver,Placenta,Skin
