CD39 (PN0464) Nb-FC recombinant antibody
- 货号：YA0348
- 应用：ELISA
- 种属：Human
- 简介：
- >>Purine metabolism;>>Pyrimidine metabolism;>>Metabolic pathways;>>Nucleotide metabolism;>>Epstein-Barr virus infection
- 蛋白名称：
- Ectonucleoside triphosphate diphosphohydrolase 1
- 免疫原：
- Purified recombinant Human CD39
- 特异性：
- This recombinant monoclonal antibody can detects endogenous levels of CD39 protein.
- 组成：
- Phosphate-buffered solution
- 来源：
- Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
- 纯化工艺：
- Recombinant Expression and Affinity purified
- 浓度：
- Please check the information on the tube
- 储存：
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- 其他名称：
- ENTPD1;CD39;Ectonucleoside triphosphate diphosphohydrolase 1;NTPDase 1;Ecto-ATP diphosphohydrolase 1;Ecto-ATPDase 1;Ecto-ATPase 1;Ecto-apyrase;Lymphoid cell activation antigen;CD39;CD39 nanobody;
- 背景：
- The protein encoded by this gene is a plasma membrane protein that hydrolyzes extracellular ATP and ADP to AMP. Inhibition of this protein's activity may confer anticancer benefits. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015],
- 功能：
- catalytic activity:ATP + 2 H(2)O = AMP + 2 phosphate.,cofactor:Calcium.,cofactor:Magnesium.,function:In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation. Hydrolyzes ATP and ADP equally well.,PTM:Palmitoylated in the N-terminal part.,PTM:The N-terminus is blocked.,similarity:Belongs to the GDA1/CD39 NTPase family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. The vascular isoform and the placental isoform II are present in both placenta and umbilical vein, whereas placental isoform I is present in placenta only.,
- 细胞定位：
- Membrane ; Multi-pass membrane protein .
- 组织表达：
- Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. Isoform 1 and isoform 3 are present in both placenta and umbilical vein, whereas isoform 2 is present in placenta only.
