CD34 (PN0490) Nb-FC recombinant antibody
- 货号：YA0320
- 应用：FCM;ELISA
- 种属：Human
- 蛋白名称：
- Hematopoietic progenitor cell antigen CD34 (CD antigen CD34)
- 免疫原：
- Purified recombinant Human CD34
- 特异性：
- This recombinant monoclonal antibody can detects endogenous levels of CD34 protein.
- 组成：
- Phosphate-buffered solution
- 来源：
- Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
- 稀释：
- ELISA 1:5000-100000;FCM 1-2μg/Test
- 纯化工艺：
- Recombinant Expression and Affinity purified
- 浓度：
- Please check the information on the tube
- 储存：
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- 其他名称：
- CD34 antibody;CD34 antigen antibody;CD34 molecule antibody;CD34_HUMAN antibody;Cluster designation 34 antibody;cluster of differentiation 34 antibody;Hematopoietic progenitor cell antigen CD34 antibody;HPCA1 antibody;Mucosialin antibody;OTTHUMP00000034733 antibody;OTTHUMP00000034734 antibody;CD34 nanobody;
- 背景：
- The protein encoded byThis gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells.This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found forThis gene. [provided by RefSeq, Aug 2011]
- 功能：
- alternative products:Both isoforms are expressed on the cell surface. CD34-T/CD34-F ratio increases with cell differentiation,developmental stage:On early hematopoietic progenitor cells.,disease:Abnormal CD34 expression in leukemogenesis.,Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.,online information:CD34 entry,PTM:Highly glycosylated.,PTM:Phosphorylated on serine residues by PKC.,similarity:Belongs to the CD34 family.,tissue specificity:Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.,
- 细胞定位：
- Membrane; Single-pass type I membrane protein.
- 组织表达：
- Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.
