CD326/EPCAM (PN0559) Nb-FC recombinant antibody
- 货号：YA0298
- 应用：ELISA
- 种属：Human
- 基因名称：
- EPCAM GA733-2 M1S2 M4S1 MIC18 TACSTD1 TROP1
- 蛋白名称：
- Epithelial cell adhesion molecule (Ep-CAM) (Adenocarcinoma-associated antigen) (Cell surface glycoprotein Trop-1) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Epithelial glycopro
- 免疫原：
- Purified recombinant Human CD326
- 特异性：
- This recombinant monoclonal antibody can detects endogenous levels of CD326/EPCAM protein.
- 组成：
- Phosphate-buffered solution
- 来源：
- Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
- 纯化工艺：
- Recombinant Expression and Affinity purified
- 浓度：
- Please check the information on the tube
- 储存：
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- 其他名称：
- 17 1A;323/A3;Adenocarcinoma associated antigen;Adenocarcinoma-associated antigen;Antigen identified by monoclonal antibody AUA1;AUA1;CD326;CD326 antigen;Cell surface glycoprotein Trop 1;Cell surface glycoprotein Trop 2;Cell surface glycoprotein Trop-1;CO 17A;CO17 1A;CO17A;DIAR5;EGP 2;EGP;EGP2;EGP314;EGP40;Ep CAM;Ep-CAM;EPCAM;EPCAM_HUMAN;Epithelial cell adhesion molecule;Epithelial Cell Adhesion Molecule Intracellular Domain (EpCAM-ICD);Epithelial cell surface antigen;Epithelial cellular adhesion molecule;Epithelial glycoprotein 1;Epithelial glycoprotein 314;Epithelial glycoprotein;ESA;GA733 1;GA733 2;GA733-2;gastrointestinal tumor-associated antigen 2;35-KD glycoprotein;hEGP 2;hEGP314;HNPCC8;Human epithelial glycoprotein 2;KS 1/4 antigen;KS1/4;KSA;Lymphocyte antigen 74;M1S 1;M1S2;M4S1;Major gastrointestinal tumor associated protein GA733 2;Major gastrointestinal tumor-associated protein GA733-2;Membrane component chromosome 4 surface marker (35kD glycoprotein);Membrane component;chromo
- 背景：
- This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins.This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations inThis gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
- 细胞定位：
- Lateral cell membrane ; Single-pass type I membrane protein . Cell junction, tight junction . Colocalizes with CLDN7 at the lateral cell membrane and tight junction. .
- 组织表达：
- Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma.
