CD3 (PN0621) Nb-FC recombinant antibody
- 货号：YA0259
- 应用：ELISA
- 种属：Human
- 蛋白名称：
- T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain) (CD antigen CD3e)
- 免疫原：
- Purified recombinant Human CD3
- 特异性：
- This recombinant monoclonal antibody can detects endogenous levels of CD3 protein.
- 组成：
- Phosphate-buffered solution
- 来源：
- Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
- 纯化工艺：
- Recombinant Expression and Affinity purified
- 浓度：
- Please check the information on the tube
- 储存：
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- 其他名称：
- T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain;CD antigen CD3e);CD3 nanobody;
- 背景：
- The protein encoded byThis gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex.This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects inThis gene cause immunodeficiency.This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
- 功能：
- The CD3 complex mediates signal transduction.,online information:CD3E mutation db,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 1 ITAM domain.,subunit:The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.,
- 细胞定位：
- Cell membrane ; Single-pass type I membrane protein .
