CD27 (PN0509) Nb-FC recombinant antibody
- 货号：YA0228
- 应用：ELISA
- 种属：Human
- 蛋白名称：
- CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (T14) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27)
- 免疫原：
- Purified recombinant Human CD27
- 特异性：
- This recombinant monoclonal antibody can detects endogenous levels of CD27 protein.
- 组成：
- Phosphate-buffered solution
- 来源：
- Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
- 纯化工艺：
- Recombinant Expression and Affinity purified
- 浓度：
- Please check the information on the tube
- 储存：
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- 其他名称：
- CD 27 antibody;CD27 antibody;CD27 antigen antibody;CD27 molecule antibody;CD27_HUMAN antibody;CD27L receptor antibody;LPFS2 antibody;MGC20393 antibody;OTTHUMP00000238557 antibody;S152 antibody;T cell activation antigen CD27 antibody;T cell antivation antigen S152 antibody;T-cell activation antigen CD27 antibody;T14 antibody;TNFRSF 7 antibody;TNFRSF7 antibody;TNFSF7 antibody;Tp 55 antibody;Tp55 antibody;Tumor necrosis factor receptor superfamily member 7 antibody;CD27 nanobody;
- 背景：
- CD27 molecule(CD27) Homo sapiens The protein encoded byThis gene is a member of the TNF-receptor superfamily.This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process ofThis receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind toThis receptor and is thought to play an important role in the apoptosis induced byThis receptor. [provided by RefSeq, Jul 2008]
- 功能：
- Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
- 细胞定位：
- Membrane; Single-pass type I membrane protein.
- 组织表达：
- Found in most T-lymphocytes.
