CD223/LAG-3 (PN0566) Nb-FC recombinant antibody
- 货号：YA0192
- 应用：ELISA
- 种属：Human
- 蛋白名称：
- Lymphocyte activation gene 3 protein (LAG-3) (CD antigen CD223) [Cleaved into: Secreted lymphocyte activation gene 3 protein (sLAG-3)]
- 免疫原：
- Purified recombinant Human CD223
- 特异性：
- This recombinant monoclonal antibody can detects endogenous levels of CD223/LAG-3 protein.
- 组成：
- Phosphate-buffered solution
- 来源：
- Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
- 纯化工艺：
- Recombinant Expression and Affinity purified
- 浓度：
- Please check the information on the tube
- 储存：
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- 其他名称：
- LAG3;FDC;Lymphocyte activation gene 3 protein;LAG-3;Protein FDC;CD223;CD223 nanobody;LAG-3 nanobody
- 背景：
- Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008]
- 功能：
- Involved in lymphocyte activation. Binds to HLA class-II antigens.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:On cell surface of activated NK and T-lymphocytes.,
- 细胞定位：
- [Lymphocyte activation gene 3 protein]: Cell membrane ; Single-pass type I membrane protein .; [Secreted lymphocyte activation gene 3 protein]: Secreted . Produced following cleavage of the main chain. .
- 组织表达：
- Primarily expressed in activated T-cells and a subset of natural killer (NK) cells.
