• 靶点：
• CD206

• 基因名称：
• MRC1 CLEC13D CLEC13DL MRC1L1

• 蛋白名称：
• Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein

• Human Gene Id：
• 4360

• Human Swiss Prot No：
• P22897

• 免疫原：
• Purified recombinant Human CD206

• 特异性：
• This recombinant monoclonal antibody can detects endogenous levels of CD206 protein.

• 组成：
• Phosphate-buffered solution

• 来源：
• Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell

• 稀释：
• ELISA 1:5000-100000

• 纯化工艺：
• Recombinant Expression and Affinity purified

• 浓度：
• Please check the information on the tube

• 储存：
• -15°C to -25°C/1 year(Avoid freeze / thaw cycles)

• 其他名称：
• MRC1;CLEC13D;CLEC13DL;MRC1L1;Macrophage mannose receptor 1;MMR;C-type lectin domain family 13 member D;C-type lectin domain family 13 member D-like;Macrophage mannose receptor 1-like protein 1;CD206

• 背景：
• The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded byThis gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]

• 功能：
• Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.,miscellaneous:CRDs 1-3 have at most very weak affinity for carbohydrate. CRD 4 shows the highest affinity binding and has multispecificity for a variety of monosaccharides. At least 3 CRDs (4, 5, and 7) are required for high affinity binding and endocytosis of multivalent glycoconjugates.,online information:Macrophage mannose receptor,similarity:Contains 1 fibronectin type-II domain.,similarity:Contains 1 ricin B-type lectin domain.,similarity:Contains 8 C-type lectin domains.,

• 细胞定位：
• Endosome membrane ; Single-pass type I membrane protein . Cell membrane ; Single-pass type I membrane protein .

• 组织表达：
• Milk,Placenta,Testis

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