CD185 (PN0053) Nb-FC recombinant antibody
- 货号：YA0142
- 应用：FCM;ELISA
- 种属：Human
- 蛋白名称：
- C-X-C chemokine receptor type 5 (CXC-R5) (CXCR-5) (Burkitt lymphoma receptor 1) (Monocyte-derived receptor 15) (MDR-15) (CD antigen CD185)
- 免疫原：
- Purified recombinant Human CD185
- 特异性：
- This recombinant monoclonal antibody can detects endogenous levels of CD185 protein.
- 组成：
- Phosphate-buffered solution
- 来源：
- Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
- 稀释：
- ELISA 1:5000-100000;FCM 1-2μg/Test
- 纯化工艺：
- Recombinant Expression and Affinity purified
- 浓度：
- Please check the information on the tube
- 储存：
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- 其他名称：
- BLR1;MDR15;BLR 1 antibody;BLR1 antibody;Burkitt lymphoma receptor 1 antibody;Burkitt lymphoma receptor 1 GTP binding protein antibody;Burkitt lymphoma receptor 1;GTP binding protein (chemokine (C-X-C motif) receptor 5) antibody;C X C chemokine receptor type 5 antibody;C-X-C chemokine receptor type 5 antibody;CD 185 antibody;CD185 antibody;CD185 antigen antibody;Chemokine (C-X-C motif) receptor 5 antibody;Chemokine C X C motif receptor 5 antibody;Chemokine CXC motif receptor 5 antibody;Chemokine receptor 5 antibody;CXC chemokine receptor type 5 antibody;CXC R5 antibody;CXC-R5 antibody;CXCR 5 antibody;CXCR-5 antibody;Cxcr5 antibody;CXCR5_HUMAN antibody;MDR 15 antibody;MDR-15 antibody;MDR15 antibody;MGC117347 antibody;Monocyte derived receptor 15 antibody;Monocyte-derived receptor 15 antibody;
- 背景：
- CD185, also known as CXCR5, is a 42 kD G-protein coupled receptor with seven transmembrane regions. CXCR5 is expressed by mature B cells, follicular helper T cells, Burkitt’s lymphoma cells and a subset of neurons, and mediates cell migration to the B cell follicles in the secondary lymphoid organs. The ligand of CXCR5 is CXCL13 (BLC).
- 功能：
- Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.
- 细胞定位：
- Cell membrane; Multi-pass membrane protein.
- 组织表达：
- Expression in mature B-cells and Burkitt lymphoma cells.
