• 靶点：
• CD134

• 基因名称：
• TNFRSF4 TXGP1L

• 蛋白名称：
• Tumor necrosis factor receptor superfamily member 4 (ACT35 antigen) (OX40L receptor) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD antigen CD134)

• Human Gene Id：
• 7293

• Human Swiss Prot No：
• P43489

• 免疫原：
• Purified recombinant Human CD134

• 特异性：
• This recombinant monoclonal antibody can detects endogenous levels of CD134 protein.

• 组成：
• Phosphate-buffered solution

• 来源：
• Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell

• 稀释：
• ELISA 1:5000-100000

• 纯化工艺：
• Recombinant Expression and Affinity purified

• 浓度：
• Please check the information on the tube

• 储存：
• -15°C to -25°C/1 year(Avoid freeze / thaw cycles)

• 其他名称：
• ACT 35 antibody;ACT35 antibody;ACT35 antigen antibody;ATC35 antigen antibody;CD 134 antibody;CD134 antibody;CD134 antigen antibody;IMD16 antibody;Lymphoid activation antigene ACT35 antibody;OX 40 antibody;OX40 antibody;OX40 antigen antibody;OX40 cell surface antigen antibody;OX40 homologue antibody;OX40L receptor antibody;TAX transcriptionally activated glycoprotein 1 receptor antibody;TAX transcriptionally-activated glycoprotein 1 receptor antibody;TNF receptor superfamily member 4 antibody;TNFRSF 4 antibody;TNFRSF4 antibody;TNR4_HUMAN antibody;Tumor necrosis factor receptor superfamily member 4 antibody;Txgp 1l antibody;Txgp1 antibody;Txgp1l antibody

• 背景：
• CD134, also known as OX40 and TNFRSF4, is a 50 kD type I transmembrane glycoprotein. It is a member of the TNF receptor family. OX40 is expressed on activated T lymphocytes including Th1, Th2, Th17, and Treg cells. The interaction of OX40 with OX40L results in B cell proliferation and antibody secretion, regulation of primary T cell expansion, and T cell survival. OX40 influences the size of the T cell memory pool and regulation of CD4+ T cell tolerance.

• 功能：
• Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity. (Microbial infection) Acts as a receptor for human herpesvirus 6B/HHV-6B.

• 细胞定位：
• Membrane; Single-pass type I membrane protein.

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